1. Create account.

• Register here, or login if you already have account
• Create a worker that will be used by the miner to login

2. Download a miner.

• Windows users: download and unzip: Cgminer-3.2.2-windows.zip.
• Linux users: download and unpack : Cgminer-3.2.2 (64bit)
• Mac OS X users: precompiled binaries are available here.

3. Configure your miner.

Settings for Stratum (recommended):

STRATUM:	stratum+tcp://yourdomain.com
PORT:	3333
Username:	Weblogin.Worker
Password:	Worker Password

If you use a command-line miner, type:

	./cgminer --scrypt -o stratum+tcp://yourdomain.com:3333 -u Weblogin.Worker -p Worker password

If you want, you can create additional workers with usernames and passwords of your choice Here

4. Create a Litecoin address to recieve payments.

• Downloading the client & block chain: Download the Litecoin client from the here.
  Generate a new address and input it on your account page to receive payments.

5. Advanced cgminer settings / FAQ

• Scrypt readme
• Don't set intensity too high, I=11 is standard and safest. Higher intensity takes more GPU RAM. Check for hardware errors in cgminer (HW). HW=0 is good, otherwise lower intensity :)
• Set shaders according to the readme (or look at your graphic cards specifications). Cgminer uses this value at first run to calculate thread-concurrency. Easiest way to get this optimized is to use same settings as others have used here: here.
• There's also an interesting project which gives you a GUI for cgminer. Windows only it seems.
• Here's a great guide how to get up and running with Xubuntu.